Éder Militão, Rodrygo and Lucas Vázquez all had to be substituted during Real Madrid’s 4-0 LaLiga win over Osasuna on Saturday, adding to the club’s extensive injury list.

Vinícius Júnior scored a hat trick for Madrid, and Jude Bellingham netted his first goal of the season, but the victory was soured by the triple injury blow to Militão, Rodrygo and Vázquez.

“It was a good game, we controlled it well from the start,” coach Carlo Ancelotti said in his post-match news conference. “From when we opened the scoring, the team looked good. The shame is the injuries in the first half. We’re assessing them now, and we’ll see.

“Three injuries in the first half is quite strange. The calendar is demanding and doesn’t allow the players to rest, they go into games tired, so the risk of injuries is higher.”

Forward Rodrygo — who had only just returned to the team after recovering from a hamstring problem — was withdrawn in the 20th minute at the Bernabéu, and replaced by Brahim Díaz.

Centre-back Militão needed treatment 10 minutes later before being stretchered off, with youngster Raul Asencio being introduced in his place.

Full-back Vázquez was then withdrawn at halftime, and was replaced by Luka Modric.

Madrid are short in defence, with Dani Carvajal out for the season with a serious injury, and David Alaba not yet fully recovered from his ACL tear.

They are also without goalkeeper Thibaut Courtois, who has a thigh injury, and midfielder Aurélien Tchouaméni — who sometimes fills in at the back — who has an ankle sprain.

“We have to thank the academy for the work they’ve done with [Asencio],” Ancelotti said. “He’s a player we need at this time … Raul has been doing well with [reserve team] Castilla and now he’ll be with us.”

Ancelotti wouldn’t say if the string of injuries made January signings more likely.

“We’ll assess it in the coming months,” he said. “Right now there’s nothing we can do. We’ll evaluate what we can do in January.”

Madrid had gone into the Osasuna game under pressure, after being beaten twice at home in their previous two matches, against Barcelona and AC Milan.

They now have a two-week break, before returning to action against Leganés on Nov. 24 and travelling to Anfield to play Liverpool in the Champions League on Nov. 27.

Saturday’s win leaves Madrid six points behind LaLiga leaders Barcelona, who play on Sunday.